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Data represent the percentage of animals lacking liver disease (liver biopsy completed) having a negative test result. Additional data from this large clinical population are provided in other figures in this article. ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, γ-glutamyltransferase.
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The American and European guidelines recommend oral anticoagulant therapy with warfarin with varying durations from 3-6 months. However, there are no prospective trials comparing warfarin and direct oral anticoagulants (DOACs) as anticoagulation in the treatment of LV thrombus.The consensus of this writing group, which is based on retrospective registry data and small, prospective observational studies, is for anticoagulation (VKA or DOAC) in patients with LV thrombus in the setting of DCM for at least 3 to 6 months, with discontinuation if LVEF improves to >35% (assuming resolution of the LV thrombus) or if .
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